CALIBRATION OF MELTING POINT APPARATUS

• OBJECTIVE:

• To lay down the procedure for Calibration of Melting Point Apparatus.

• SCOPE:

This SOP is applicable to the procedure for Calibration of Melting Point Apparatus at {Company Name} {Location}.

• RESPONSIBILITY:

• Executive/Designee Quality Control is responsible to calibrate the instrument as per SOP.
• Head QC: Ensure the compliance of SOP.

• ACCOUNTABILITY:

             QA Head shall be Accountable for implementation of SOP.

• PROCEDURE:

• A melting point apparatus is a scientific instrument used to determine the melting point of a substance. The melting point is the temperature at which a solid changes into a liquid. It is an important physical property of a substance and can be used to identify unknown substances, to test the purity of a substance, and to monitor the progress of a chemical reaction.

• Operate the instrument as per SOP.
  • Fill dry powder of Melting Point Reference Standards (USP) in the capillaries individually.
  • Insert the capillaries one by one.
  • Observe the melting range of each material
  • Melting range should be compared with values given below:

• Record the results in the format attached (Format-I).
  • If the calibration is not proper, repeat the procedure and report the results to the department Head for taking an appropriate action.
  • Frequency: Half yearly.

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• REFERENCES:

Not Applicable

• ANNEXURES: 

        ENCLOSURES: SOP Training Record.

•  DISTRIBUTION:

• Controlled Copy No. 01  :          Head Quality Assurance
• Controlled Copy No. 02  :         Head Quality Control
• Master Copy                    :          Quality Assurance Department

• ABBREVIATIONS:

• REVISION HISTORY:             

CHANGE HISTORY LOG

Annexure-I
CALIBRATION RECORD OF MELTING POINT APPARATUS

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