CLEANING OF GLASSWARE USED IN CHEMICAL AND INSTRUMENTATION ANALYSIS

• OBJECTIVE:

To lay down the procedure for cleaning of Glassware used for analytical purposes.

• SCOPE:

This SOP is applicable for the procedure for cleaning of Glassware used for analytical purposes at {Company /name} {Location}.

• RESPONSIBILITY:

• Officer/Executive/Designee Quality Control – Shall be responsible for cleaning of glassware as per SOP.
• Head/Designee Quality Control – Shall be responsible for ensuring compliance as per SOP.

• ACCOUNTABILITY:

QA Head shall be Accountable for implementation of SOP.

• PROCEDURE:

• After completion of analytical work, keep all the glassware in tray and transfer it into washing area.  
• General glassware:
• Wear a rubber apron, safety goggles, and rubber hand gloves.
• Empty the glassware under the running tap water.
• Remove any external marking on glassware with solvent.
• Clean the glassware with suitable nylon brush by using cleaning solution “Teepol solution or Equivalent”.
• Clean oily and greasy content by using 70% nitric acid solution.
• Wash the glassware with tap water up to foaming not observed in water by vigorous shaking.
• Rinse the glassware with purified water.
• Ensure complete removal of cleaning solution by visual checking.
• Keep the glassware in inverted position for water drain out from glassware.
• Finally, the Glassware shall be rinsed with acetone and dried at 40°C.
• After drying the Glassware shall be removed and stored in their designated places.
• Ensure cleaning of glassware by visual inspection before use for analysis.
• Pipette washing:
• Rinse used pipette with tap water by tubing connected to water line.
• Rinse it 2-3 times in plastic cylinder having cleaning solution.
• “Teepol or equivalent”.Rinse it with tap water by tubing connected to water line up to foaming not observed in pipette.
• Finally rinse the pipette with purified water.
• Ensure complete removal of cleaning solution from pipette by visual checking.
• Keep clean pipette in pipette stand for water drain out.
• Finally, the Glassware shall be rinsed with acetone and dried at 40°C.
• Transfer clean and dry pipettes in their designated places.
• Ensure cleaning of pipette by visual inspection before use for analysis.
• Burette washing:
• Rinse used burette with tap water by tubing connected to waterline.
• Rinse it with tap water by tubing connected to waterline up to foaming not observed in Burette.
• Finally rinse the burette with purified water.
• Ensure complete removal of cleaning solution from burette by visual checking.
• Keep clean burette in burette stand for water drain out.
• Dry it as per the general procedure mentioned above.
• Transfer clean and dry burette in their designated places.

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• REFERENCES:

Not Applicable

• ANNEXURES: 

Not Applicable

      ENCLOSURES: SOP Training Record.

• DISTRIBUTION:

• Controlled Copy No. 01  :          Head Quality Assurance
• Controlled Copy No. 02  :         Head Quality Control
• Master Copy                    :          Quality Assurance Department

• ABBREVIATIONS:

• REVISION HISTORY:              

CHANGE HISTORY LOG

Click the link to download word file copy of this document:
https://pharmaguidehub.com/product/cleaning-of-glassware-used-in-chemical-and-instrumentation-analysis/